7 comments

  • kindkang2024 4 minutes ago

    Know your unknown: that is highest.

    Mistake your unknown for known: that is sickness.

    Only be sick of the sickness, and you are not sick.

    The sage is not sick: sick of the sickness, he is not sick.

    — Laozi, Tao Te Ching, Chapter 71

  • sxg an hour ago

    Non-physicians would be shocked at how many medications we routinely use that have no agreed-upon mechanism of action. It’s not just cancer drugs—we really don’t know how many other drugs including anesthetics work despite their critical importance. Historically in medicine, you just treat these meds like a black box. If a reasonable dose produces a reliable outcome in a large number of people with no major side effects, you consider the drug reasonably safe to use.

      kspacewalk2 15 minutes ago

      This is the crux of the difference between evidence-based medicine and science-based medicine. Is knowing that it works enough, or must you understand the scientific mechanism?

        alwa 4 minutes ago

        I’m having trouble finding more background on the “science-based medicine” you refer to. Wikipedia refers to a website operated by two members of the “New England Skeptical Society.” The disambiguation link redirects to “evidence-based medicine.”

        https://en.wikipedia.org/wiki/Science-Based_Medicine

        Is this the school of thought that you mean?

        eviks 9 minutes ago

        What a weird terminology given the fact that evidence is the core component of science

  • bitwize 5 minutes ago

    The current state of things is that AI has put us on the cusp of a future exactly as Kevin Flynn said in Tron: Legacy: "Disease? History! Science, philosophy... every idea man has ever had about the universe up for grabs!" We don't need to understand every bit of it to benefit from it; understanding will come with time, when our meager minds are ready for it.

    We should be joyful and excited. Instead, those of us who gatekept knowledge, including us software engineers and even mathematicians, are viewing this future with fear and trepidation. Because we lose our power, prestige, and leverage over the rest of society.

  • wonnage 5 minutes ago

    > If AI conjures up a cocktail to cure cancer and we don't know how it works, but it passes a phase 3 trial, you can bet we will be on our knees thanking it, or more likely giving a standing ovation at our plenary session.

    Ironic that his vaccine skepticism evaporates when there’s an opportunity to be contrarian. Or maybe he’s changed his mind now that the overwhelming evidence of the Covid vaccines proves he was full of shit