> Our general approach is to automate the experimental loop. We think this approach is broadly applicable across many different fields of science and engineering. We’ll initially focus on ML research and engineering, but believe the approach can help with important subproblems in nearly every one of the fourteen <at>NAE Grand Challenge problems. We think doing this well requires strong expertise in machine learning as well as large-scale systems.
The problem is all these new labs don't have any competitive advanatge amongst each other, talent can only take one so far, though Jeff is a legend no doubt.
Models are commodities the applications eg. BaseTen, OpenRouter should capture the value.
Model routers - send all of your data through a third party who totally swears not to peek at it.
If youre doing anything worthwhile (advanced research, classified work, high value industrial research, health data, or anything high value) then sending your data through a third party like that is insane.
This is very cool. It might be a new scientific revolution to have computer-driven discovery. So often we find things that are "this could have been done 20 years ago" and with an indefatigable searcher perhaps we'll close all those things. Though it does remind me of that Ted Chiang (I think) story where humans and superhumans coexist and all the science of the former is meta-studies of the work of the latter.
I’ve always felt that the idea that science is bottlenecked and therefore needs more automation only works for a very narrow definition of what science is, and entails a very specific view on what it should be.
> only works for a very narrow definition of what science is
And so does academia. It's just that instead of AI and robotics, PhD students are thrown onto problems that are in large parts slightly tweaked reconfigurations of similar experiments.
Especially in chemistry, biochemistry, material sciences there is a large space of discoveries that are barely "novel" in an intellectually stimulating way, but still highly valuable that can be explored orders of magnitudes faster than is currently the case.
Yep. A communications professor where I did my MS says a 200usd/mo claude sub (which ant gives for free) does as much work as 5 grad students. It's mostly like you said, trying out new ideas rapidly.
This reminds me of Three body problem and how the scientist discovered the high strength wire was through quick physical experiments and use them as input to an AI model to determine if it works.
> we have pioneered massive scale computing and led the creation of critical infrastructure, products, and foundational AI advances that the world relies on, including multiple generations of Google Search, Google Ads, Google News, Google Translate, Google File System, MapReduce, BigTable, Spanner, TensorFlow, Pathways, TPUs, AlphaChip, AlphaStar, AlphaCode, AlphaFold, Gemini, model distillation, mixture-of-experts model architectures, word2vec, sequence-to-sequence models, chain of thought reasoning, neural architecture search, and multiple generations of Large Language Models (LLMs) among others.
I'm skeptical of any Engineering loop that doesn't include reality (as in touch grass) feedback. Pure logic and reasoning is the domain of Maths and Science (philosophy). Surely it will work, but it will not "be able to solve any learning loop".
From Jeff's twitter post:
> Our general approach is to automate the experimental loop. We think this approach is broadly applicable across many different fields of science and engineering. We’ll initially focus on ML research and engineering, but believe the approach can help with important subproblems in nearly every one of the fourteen <at>NAE Grand Challenge problems. We think doing this well requires strong expertise in machine learning as well as large-scale systems.
See also: https://www.nae.edu/20782/grand-challenges-project
Those 14 are:
NAE Grand Challenges for Engineering
1. Make Solar Energy Economical
2. Provide Energy from Fusion
3. Develop Carbon Sequestration Methods
4. Manage the Nitrogen Cycle
5. Provide Access to Clean Water
6. Restore and Improve Urban Infrastructure
7. Advance Health Informatics
8. Engineer Better Medicines
9. Reverse Engineer the Brain
10. Prevent Nuclear Terror
11. Secure Cyberspace
12. Enhance Virtual Reality
13. Advance Personalized Learning
14. Engineer the Tools of Scientific Discovery
Acquisition back by Google in 3 years, with nothing to show for it. VCs will make a ton.
My thoughts exactly
and... the VC is Google.
Gotta compensate them somehow.
The site itself is really leaning into the “made with Fable” aesthetic
The problem is all these new labs don't have any competitive advanatge amongst each other, talent can only take one so far, though Jeff is a legend no doubt.
Models are commodities the applications eg. BaseTen, OpenRouter should capture the value.
https://taikhooms.substack.com/p/why-openrouter-can-be-the-n...
The company is developing an application, or a class of applications. Not a new model.
Model routers - send all of your data through a third party who totally swears not to peek at it.
If youre doing anything worthwhile (advanced research, classified work, high value industrial research, health data, or anything high value) then sending your data through a third party like that is insane.
"Our mission is straightforward" continued by the most complex sentence on that page. Wondering what the definition of straightforward is now
This is very cool. It might be a new scientific revolution to have computer-driven discovery. So often we find things that are "this could have been done 20 years ago" and with an indefatigable searcher perhaps we'll close all those things. Though it does remind me of that Ted Chiang (I think) story where humans and superhumans coexist and all the science of the former is meta-studies of the work of the latter.
> It might be a new scientific revolution to have computer-driven discovery.
And ... it might not.
True, nothing might be anything. But I'm an optimist :)
Oh wow, that's a blow to Google, what's with the talent scarcity in ML. Though if this goes anywhere Google will likely buy them back.
Google down $160Bn so far since the leaving announcements. Those are some valuable people!
Google is literally at the same stock price it was on Monday. This is a normal daily fluctuation for them.
Google is backing it.
For sure made with Claude code for front end, but I’m excited to see where they go
I’ve always felt that the idea that science is bottlenecked and therefore needs more automation only works for a very narrow definition of what science is, and entails a very specific view on what it should be.
> only works for a very narrow definition of what science is
And so does academia. It's just that instead of AI and robotics, PhD students are thrown onto problems that are in large parts slightly tweaked reconfigurations of similar experiments.
Especially in chemistry, biochemistry, material sciences there is a large space of discoveries that are barely "novel" in an intellectually stimulating way, but still highly valuable that can be explored orders of magnitudes faster than is currently the case.
Yep. A communications professor where I did my MS says a 200usd/mo claude sub (which ant gives for free) does as much work as 5 grad students. It's mostly like you said, trying out new ideas rapidly.
Lets keep your comment out of the VC pitch deck shall we?
This reminds me of Three body problem and how the scientist discovered the high strength wire was through quick physical experiments and use them as input to an AI model to determine if it works.
By the middle of the 2030's the world we live in will be unrecognizable.
I agree, for better or for worse.
If I had to bet my money, it would be on "for worse".
National Labs in the US have been doing this for a while now. I feel like the private sector will take the lead soon.
When they say experiments, do they mean using physics simulators?
you people worship money and money only and cannot see vaporware because of it.
I am available for hire.
Related:
Jeff Dean leaving Alphabet
https://news.ycombinator.com/item?id=49184746
Computation is not the hard part of discovery.
> we have pioneered massive scale computing and led the creation of critical infrastructure, products, and foundational AI advances that the world relies on, including multiple generations of Google Search, Google Ads, Google News, Google Translate, Google File System, MapReduce, BigTable, Spanner, TensorFlow, Pathways, TPUs, AlphaChip, AlphaStar, AlphaCode, AlphaFold, Gemini, model distillation, mixture-of-experts model architectures, word2vec, sequence-to-sequence models, chain of thought reasoning, neural architecture search, and multiple generations of Large Language Models (LLMs) among others.
holy shit. I've known this, but...
I'm skeptical of any Engineering loop that doesn't include reality (as in touch grass) feedback. Pure logic and reasoning is the domain of Maths and Science (philosophy). Surely it will work, but it will not "be able to solve any learning loop".
How is that different than video input?
There are over 2 dozen known senses to reality. Video input is a fraction of a sense.
https://en.wikipedia.org/wiki/Sense#Artificial_sensation_and...
Is this a joke? Site is not loading for me.
So Ralph Wiggum in a suit?