Confused a bit by the article: it mentions human trials began in september 2024, but also that the trials that might prove it working are yet to start?
I think it's just poorly written. If you go to the source[1] the trial period was planned from September 2024 to August 2025, and the submission says people are "undergoing" a trial. Perhaps it got delayed, or, more likely IMHO, the trial period is over and they're studying the data so haven't made reached a conclusion yet.
Aren't the shape/size/placement/etc. of human teeth fairly unique across different individuals? At least unique enough to use dental records to identify bodies.
I don't see if mentioned in TFA, but if new human teeth can be grown is it expected that the new ones will just grow in "correctly" to fit a person's mouth?
> At least unique enough to use dental records to identify bodies.
Yes but in comparative dental analysis they use ante-mortem dental records to compare with post-mortem remains. It's not like DNA where you can record it once and then use that to match samples decades later in a database. In order to have a high confidence in a match, recent x-rays and records of dental work like fillings, crowns, etc. work best.
And no it is not expected. It's one of the primary challenges with bringing these kinds of drugs to market, as hyperdontia is already relatively common among humans (I had an incisor growing at the roof of my mouth an inch behind my row of teeth). Most successful applications of these tooth regrowth drugs tend to place them near the root of missing teeth hoping that the cellular growth signaling mechanisms are still working.
I've been taking vitamin k2 mk4 at 45mg a day for over a year now. My teeth feel gr8. Now I need to get some of this stuff to have super human chompers.
Confused a bit by the article: it mentions human trials began in september 2024, but also that the trials that might prove it working are yet to start?
I think it's just poorly written. If you go to the source[1] the trial period was planned from September 2024 to August 2025, and the submission says people are "undergoing" a trial. Perhaps it got delayed, or, more likely IMHO, the trial period is over and they're studying the data so haven't made reached a conclusion yet.
[1]: https://www.kitano-hp.or.jp/info/20240503
Aren't the shape/size/placement/etc. of human teeth fairly unique across different individuals? At least unique enough to use dental records to identify bodies.
I don't see if mentioned in TFA, but if new human teeth can be grown is it expected that the new ones will just grow in "correctly" to fit a person's mouth?
> At least unique enough to use dental records to identify bodies.
Yes but in comparative dental analysis they use ante-mortem dental records to compare with post-mortem remains. It's not like DNA where you can record it once and then use that to match samples decades later in a database. In order to have a high confidence in a match, recent x-rays and records of dental work like fillings, crowns, etc. work best.
And no it is not expected. It's one of the primary challenges with bringing these kinds of drugs to market, as hyperdontia is already relatively common among humans (I had an incisor growing at the roof of my mouth an inch behind my row of teeth). Most successful applications of these tooth regrowth drugs tend to place them near the root of missing teeth hoping that the cellular growth signaling mechanisms are still working.
Teeth wear quite a bit too, I wonder will new ones have to be pared down to fit.
This is like fusion energy. It's been 4 years away since I've been a child.
I personally regrew my teeth since I was a child. Granted, once.
Growth rate and how you don’t mess it up before it matures are problems
Scientists regrowing everything except hair. Fuck my life.
finasteride + minoxidil
Once the follicle is closed/gone, it’s gone.
Minoxidil won’t help grow hair on a patch of bold skin. After that only hair transplantation
If you don't have sides that is
And limbs.
I would say every tissue: no bones, no organs, eyes, ears, nerves, skin.
Like what can they grow?
I've been taking vitamin k2 mk4 at 45mg a day for over a year now. My teeth feel gr8. Now I need to get some of this stuff to have super human chompers.
What changes in your subjective sensation of your teeth with K2?